Juan Qin

Glutaminolysis Blockade‐Empowered Bimodal Nanodepot for Spatially Complementary Sono‐Thermal Ablation via PANoptosis and STING Activation Against Large Tumors

ABSTRACT Microwave ablation (MWA) for large hepatocellular carcinoma (HCC) is frequently compromised by non‐uniform thermal distribution and immunosuppressive niche formation. To address these challenges, we engineered an injectable bimodal nanodepot (TCPD) via catalytic crosslin...

Dual-Stimuli-Driven Calcium Nanomachines for NO-Induced Immunogenic Cell Death

Abstract Tumor blood vascular endothelial cells targeting has emerged as a powerful strategy to enhance the accumulation and penetration of nanomedicines. However, the complex tumor microenvironment, especially the newly discovered breast cancer blood vascular basement membrane,...