Joseph Irudayaraj

The urinary pathobiont Actinobaculum massiliense can generate androgens via the dirAB pathway

While overlooked during the Human Microbiome Project, characterizing the urinary microbiota in health and disease is a new frontier in microbiome science. Recent studies have associated differential abundance of bacterial taxa including Propionimicrobium lymphophilum and Actinoba...

The urinary tract commensal Peptoniphilus spp. encodes a novel 17β-hydroxysteroid dehydrogenase

ABSTRACT Microbial steroid metabolism represents an underappreciated extension of the vertebrate endocrine system, with growing evidence that host-associated microbes contribute to the diversity and bioavailability of sex steroids to human tissues. Emerging studies have linked mi...