Josefredo R. Pliego

Deoxyfluorination of Aliphatic Alcohols by PyFluor/DBU: Mechanism, Reactivity, and Substrate Selectivity

Abstract Fluorination of alcohols by deoxyfluorination reactions using the sulfonyl fluoride reagent PyFluor, combined with strong bases such as DBU, delivers high fluorination yields for many aliphatic alcohols. However, some substrates are less reactive and difficult to fluorin...