José Emiliano González Flores

Cleft Palate Surgery: Evolving Surgical Techniques and Reconstructive Principles for Oronasal Fistula and Velopharyngeal Dysfunction: A Narrative Review

Background Despite more than a century of surgical innovation, no single palatoplasty technique has demonstrated consistently superior outcomes across the spectrum of cleft palate phenotypes. Objective This review examines the historical evolution of cleft palate reconstruction a...

Biologic Therapies for Knee Osteoarthritis: A Structured Narrative Review of Joint Preservation Strategies and Clinical Outcomes

Knee osteoarthritis (KOA) is among the leading causes of chronic pain and physical disability worldwide, representing a major clinical challenge as currently available treatments primarily address symptoms rather than the biological mechanisms driving disease progression. As inte...