José Eduardo Krieger

Identifying Cardiac Autoantibody Biomarkers that Predict the Severity of Chagas Cardiomyopathy

Chagas cardiomyopathy (ChCM) affects up to 30% of patients with chronic Chagas disease and lacks reliable biomarkers for severity and conduction abnormalities. We profiled cardiac autoantibodies using 2-dimensional gel electrophoresis and mass spectrometry, followed by enzyme-lin...