Jorge González-Rodríguez

Dual‐Function Cosubstrates Enable Threonine Dehydrogenase‐Driven Chemoenzymatic Pyrrole Synthesis

ABSTRACT Preparative biocatalytic synthesis of substituted pyrroles remains challenging despite recent advances in enzymatic α‐aminoketone generation. In this study, we report a concurrent chemoenzymatic cascade to disubstituted pyrroles based on threonine dehydrogenase (ThrDH)‐c...