Jooseppi Hyvärinen

Proteomics Reveals Blood−Brain Barrier Membrane Protein Remodeling in Amyloid-β Pathology

Abstract The protective function of the blood−brain barrier (BBB) is achieved by membrane proteins expressed in the endothelial cells of brain microvessels, such as tight junction proteins, receptors, and transporters, which regulate the passage of solutes, including nutrients, d...