Jonathan N. Flak

Homeobox a4 is proapoptotic in the AC16 human cardiomyocyte cell line and a key effector of the MIAT/miR-150 axis in murine myocardial infarction

Abstract MicroRNA-150-5p (miR-150) was correlated with heart failure (HF) severity in humans. Left ventricular homeobox a4 (HOXA4) was upregulated in patients with HF. Gain-of-function mutants in myocardial infarction-associated transcript (MIAT) were associated with increased ri...