Jonathan E Owen

Zika virus produces two isoforms of the NS2A protein that play mutually exclusive roles in viral replication and virion assembly

Zika virus (ZIKV), dengue virus, and several other orthoflaviviruses cause disease outbreaks in human and animal populations worldwide. The orthoflaviviral nonstructural protein 2A (NS2A) is critical for both viral replication and virion assembly. However, due to its small size,...