Jolanta Harasiuk

Drug-Initiated Synthesis and Processing of Mupirocin–PLGA Conjugates for Biodegradable Antibacterial Scaffolds

Abstract Mupirocin–poly(lactic-co-glycolic acid) (Mup-PLGA) conjugates were developed via drug-initiated ring-opening polymerization to create biodegradable scaffolds with local antibacterial activity. Conjugate composition and molecular weight were controlled to tune degradation...

Mitochondrial Modulation as a Therapeutic Entry Point in Neurodegeneration

Mitochondrial dysfunction is a recurrent but context-dependent feature of neurodegenerative disease, and its position in the pathogenic cascade differs fundamentally between disorders. This narrative review argues that this heterogeneity, rather than mitochondrial biology itself,...