Johannes Albertus Langendijk

Subsite-specific prediction of lymphatic spread in head-and-neck cancer using a mixture of hidden Markov models

Abstract Head-and-neck squamous cell carcinomas (HNSCC) metastasize to neck lymph nodes. Radiation treatments include the elective irradiation of lymph node levels (LNLs) at risk of harboring occult (clinically undetected) metastases. We present a statistical model for personaliz...