Author
Johann E. Gudjonsson
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Recent research
- BiologyOpen access
Keratin 9 regulates mechanosensitive YAP1 signalling in palmoplantar epidermis
Steiner et al. propose that keratin 9 (K9) interacts with 14-3-3, sequestering YAP1 in the cytoplasm and inhibiting YAP1 activity. They identify dysregulated YAP in palmoplantar keratinization diseases, with K9 as a downstream regulator of YAP.