Joaquim Barreto

Effects of Dapagliflozin on the Bone of Patients with CKD on Dialysis

The effects of gliflozins on bones of CKD patients on dialysis are unknown. Recently, SGLT2 expression in bone tissue of patients with CKD has been reported. We hypothesized that dapagliflozin may act in bone cells and modulate the Klotho-FGF23 axis. This study analyzed the effec...