João Pedro Lobão Gomes Castro

Administration of nebivolol after subcutaneous ovarian autotransplantation improves neoangiogenesis, follicular survival, and growth in mice

Context As ovarian transplantation is performed without blood vessel anastomosis, its main limitation is ischemia. Nitric oxide (NO) has pro-angiogenic and antiapoptotic effects, and nebivolol, a selective β1-blocker with NO-inducing activity, may be a potential drug to improve g...