João Marcelo de Castro e Sousa

VLA-4 integrin modulates cellular responses to sorafenib in metastasis-related processes of B16F10 melanoma cells

Metastatic progression in melanoma is driven by the coordinated activity of adhesion molecules and growth factor receptors, yet the functional interplay between integrins and VEGFR-related signaling remains poorly defined. This study investigated the role of α4β1 integrin, also k...