Joanna Boros-Majewska

Th2/Th17 Inflammation: Pathogenic Drivers and Therapeutic Targets in Darier and Hailey‐Hailey Diseases

ABSTRACT Background The inherited acantholytic dermatoses Darier disease (DD) and Hailey‐Hailey disease (HHD) are characterized by a barrier dysfunction of the epidermis susceptible to inflammation and microbial infections. Objectives This study aimed at investigating the express...

Empagliflozin in GSD-Ib: Long-term safety and sustained recovery of neutrophil function including NET formation

Glycogen storage disease type Ib (GSD-Ib) engenders neutropenia and severe neutrophil dysfunction, leading to recurrent infections and inflammatory complications. Recent studies have identified intracellular accumulation of 1,5-anhydroglucitol-6-phosphate (1,5-AG6P) as a key mech...