Jinghan Hua

ARID1B promotes DNA end resection via MDC1 and co-transactivation of DNA repair genes with c-MYC in small cell lung cancer

Abstract AT-rich interactive domain-containing protein 1B (ARID1B) has been implicated in DNA damage repair; however, its precise molecular mechanisms and contributions to small cell lung cancer (SCLC) pathogenesis remain incompletely defined. In this study, analysis of clinical...