Jingdong Zhang

CYP2S1: a novel regulator of PMN-MDSC recruitment and immunotherapy resistance in esophageal squamous cell carcinoma

Chemoimmunotherapy resistance significantly limits the clinical management of esophageal squamous cell carcinoma (ESCC). To identify tumor-intrinsic regulators associated with an immunosuppressive tumor microenvironment (TME) and treatment failure, we integrated proteomic profili...