Jingchuan Ma

UBE2K-FBXO11 complex activates Wnt signaling by stabilizing β-catenin through lysine 63-linked polyubiquitination

Abstract Β-catenin is regulated by phosphorylation and lysine (K)48-linked ubiquitination, which target it for proteasomal degradation. While the degradation machinery of β-catenin, including the destruction complex, has been extensively studied, regulators that stabilize β-caten...

Low-Twist Matrix Covariants of Exterior Powers: Vanishing and Modular Phenomena

We study GL(V)-equivariant morphisms between the polynomial representations Symᵈ(ΛʳV) and End(V) ⊗ det(V) to the ℓ-th tensor power. Scalar matrices impose the necessary condition rd = nℓ, which organizes the first two determinant twists studied here. In characteristic zero we det...