Jing Zhao

Gut–Mammary Axis-Mediated Improvement of Sialylated Milk Oligosaccharide Synthesis by Polygonatum sibiricum Polysaccharide and Probiotics in Mice with Gestational Metabolic Disorders

Abstract Milk oligosaccharides (MOs) are vital for infant health but vulnerable to gestational metabolic dysfunction. To explore a new microecological intervention strategy, we established a probiotic fermentation platform coupled with a mammary epithelial cell screening model to...

Probing relaxed myosin states in hypertrophic cardiomyopathy by second harmonic-generation microscopy

This study explores the use of polarized second-harmonic generation (pSHG) to investigate myosin conformation in the relaxed state, differentiating between the actin-available, disordered (ON) state and the energy-conserving, ordered (OFF) state. By shifting the ON/OFF equilibriu...