Jing You

Toxicokinetics Reveal Structure-Related Differences in Developmental Toxicity among Typical Aromatic Disinfection Byproducts in Zebrafish Embryos

Abstract Aromatic disinfection byproducts (DBPs) are emerging contaminants generated during drinking water disinfection and exhibit higher cytotoxicity and genotoxicity than traditional aliphatic DBPs. However, in vivo toxicokinetic behavior of aromatic DBPs during sensitive deve...

Pulsed Exposure to Environmentally Relevant Concentrations of 6PPD-Q Elicits Concentration-Dependent Delayed Mortality and Prolonged Behavioral Impairment in Rainbow Trout

Abstract The tire rubber transformation product N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine-quinone (6PPD-Q) is acutely toxic to select salmonids, yet current risk thresholds are derived exclusively from constant-concentration exposure tests that fail to represent the inte...