Jinbin Liu

Transcytosis-Guided Intestinal Absorption of Ultrasmall Gold Nanoparticles for Lymphatic Entry into Systemic Circulation

Abstract The intestinal epithelial barrier severely impedes absorption of orally administered nanoparticles. Herein, we designed ultrasmall PEPT1-targeted gold nanoparticles (GP-AuNPs) using a dual-ligand strategy: Gly-Sar peptides for PEPT1 recognition on intestinal epithelial c...

Modular Orthogonal Dual-Channel Gold Nanosensor Platform for Ratiometric Imaging of Tumor-Associated Macrophage M1/M2 Polarization

Abstract The phenotypic balance between M1 and M2 tumor-associated macrophages (MΦs) governs tumor immune homeostasis and immunotherapeutic outcomes. However, in situ visualization of this polarization equilibrium remains challenging. Conventional histological and cytological app...