Jin Wang

Perioperative and Mid-Term Outcomes of Primary Versus Redo Pericardiectomy for Constrictive Pericarditis: A Single-Center Retrospective Cohort Study

Background: Direct comparative evidence between redo and primary pericardiectomy for constrictive pericarditis (CP) is limited to small, uncontrolled series. We compared perioperative and mid-term outcomes between the two cohorts and explored factors associated with all-cause dea...

Discovery andDevelopment of First-in-Class Cereblon-RecruitingRIPK1 Degraders

Abstract Receptor-interacting protein kinase 1 (RIPK1) is a critical regulator of programmed cell death and is implicated in various pathological conditions, particularly in mediating tumor resistance to immune checkpoint inhibitors (ICIs). In this study, we have pioneered the de...