Jin-Ho Jo

Impact of operon architecture on metabolic flux: highlighting gene arrangement as a critical factor for flavonoid O-rhamnoside synthesis

Abstract Background dTDP-rhamnose is synthesized by four genes ( rfbBDAC ) in Escherichia coli . While reconfiguring this operon could potentially enhance biosynthetic yields, precisely quantifying intracellular dTDP-rhamnose levels remains technically challenging. In this study,...