Jihoon Na

Ketogenic Dietary Therapies and β-Hydroxybutyrate as Modulators of Mitochondrial Function: From Molecular Mechanisms to Clinical Translation

Ketogenic dietary therapies (KDTs) have been used for a century in drug-resistant epilepsy, and β-hydroxybutyrate (BHB), the major ketone body, is recognized as a signaling metabolite. This review examines how KDTs and BHB modulate mitochondrial function and evaluates evidence su...

Health-related quality of life in patients with spinal muscular atrophy receiving nusinersen and their caregivers: a cross-sectional study

Spinal muscular atrophy (SMA) is a rare neuromuscular disorder characterized by progressive motor decline. Although nusinersen has improved survival and motor outcomes, patients and caregivers continue to face substantial medical and psychosocial challenges. As treatment goals ha...