Jieun Lim

Relative Contributions of Quinolone Resistance-Determining Region Mutations and Efflux Pump-Associated Mechanisms to Fluoroquinolone Resistance in Staphylococcus aureus Clinical Isolates and Their Associations with Virulence Gene Profiles

Background: Fluoroquinolone resistance in methicillin-resistant Staphylococcus aureus (MRSA) involves multiple mechanisms, including quinolone resistance-determining region (QRDR) mutations and efflux pump activity. However, the relationship between these resistance mechanisms an...