Jieqiong Li

Proteasome subunit-based biomarker panel for early diagnosis of acute respiratory distress syndrome and therapeutic targeting of PSMB8 in a mouse model

Acute respiratory distress syndrome (ARDS) remains a leading cause of mortality in intensive care units worldwide. Timely diagnosis and targeted treatment are critical for significantly improving patient outcomes. Plasma proteomics from 196 patients with ARDS, 100 non-ARDS pulmon...

Longitudinal profiling of upper respiratory tract microbiota and metabolome in hospitalized COVID-19 convalescents: a 3-year prospective cohort study

Long COVID is characterized by persistent, far-reaching effects in convalescent individuals, with pulmonary diffusion impairment emerging as a clinically impactful sequela affecting more than one-third of this population. The salivary microbiome and metabolome, reflecting the ora...