Jie Zhang

Prognostic significance of DNA polymerase theta and its association with immune infiltration in hepatocellular carcinoma

Abstract Background Hepatocellular carcinoma (HCC) is a common malignancy with a poor prognosis. DNA polymerase theta (POLQ) plays multiple roles in HCC, primarily in DNA damage repair, tumor progression, and resistance to chemoradiotherapy. However, the upstream and downstream s...