Jie Shen

C5aR1-positive PMN-MDSC-induced angiogenesis limits the efficacy of radiotherapy combined with Anti-PD-1 immunotherapy

Radiotherapy (RT) combined with Anti–PD-1 immunotherapy (RT + Anti-PD-1) offers synergistic potential in the treatment of colorectal cancer (CRC). However, RT + Anti-PD-1 often fails to be effective in some patients with CRC, because a subset of tumors exhibits limited responsive...

Superior Leaf Deposition and Subsequent Uptake: Nanocarrier Boosts Cyproflanilide for Enhanced Pest Control

Abstract Chemical pesticides remain indispensable for crop protection, but inefficient delivery and overapplication lead to resistance and environmental risks. Cyproflanilide is a novel meta-diamide insecticide active against a broad range of agricultural pests. Here, we develope...