Jiayi Liu

Immune-pressure redistribution in resistance to PD-1/PD-L1 blockade: mechanisms, biomarkers, and therapeutic design

PD-1/PD-L1 blockade can produce durable tumor control, yet primary, adaptive, and acquired resistance remain common. Existing accounts often catalogue resistance by cellular compartment, obscuring the coordinated nature of tumor adaptation. Here, we introduce immune-pressure redi...

Built Heritage Perception and Spatial Patterns of Tourist Affect in Dali Bai Autonomous Prefecture, China: A Social Media–Based Assessment

Against the backdrop of the concurrent processes of tourism development, spatial commercialisation, and architectural heritage conservation, identifying tourists’ cognitive images of destinations and differences in textual valence provides an important basis for evaluating the qu...

CD9 + B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression

ABSTRACT Adenoid hypertrophy (AH) is associated with excessive proliferation of germinal center B (GC‐B) cells, yet the mechanisms underlying GC regression and termination remain poorly understood. This study used single‐cell RNA sequencing (scRNA‐seq) to profile the cellular com...