Jiaqi Shi

Exploring the Coupling of Pyridines with Dearomatized 4-Alkylpyridines

Abstract We describe approaches to the synthesis of dipyridylmethane scaffolds that have potential use in medicinal chemistry. The general strategy exploits the latent nucleophilicity of 4-alkylpyridines and the inherent electrophilicity of pyridines to achieve metal-free couplin...