Jiaoyang Duan

Thioredoxin-1 induces immune tolerance against α-syn presented by MHC-II in microglia via promoting Tregs differentiation in MPTP-induced Parkinson’s disease mice

Parkinson's disease (PD) is a common neurodegenerative disease characterized by the loss of dopaminergic (DAergic) neurons in the substantia nigra pars compacta (SNpc) and the formation of Lewy bodies composed of misfolded alpha-synuclein (α-syn). A growing number of studies indi...