Jian‐Min Yue

Curvulinic Acid−Clavatol Hybrids and Curvulinic Acid Dimers with Anti-Inflammatory Activity from Penicillium sp. KYS-21

Abstract A chemical investigation of the fermentation broth of the soil-derived fungus Penicillium sp. KYS-21 led to the isolation of seven previously undescribed polyketide metabolites (1−7). Among them, penicurclavones A−D (1−4) represent the first examples of curvulinic acid−c...

Discovery of Three Macrocyclic Diterpenoid Skeletons from Croton laevigatus and Their NF-κB Inhibitory Activity

Abstract Phytochemical investigation of Croton laevigatus yielded six macrocyclic diterpenoids, craeviganoids A–F (1–6), featuring three novel carbon skeletons: two distinct types of 13-membered diterpenoid lactones (1–3) bearing a rare bridgehead alkene, and a 14-membered furano...