Jianli Ren

A dual-functional, responsive nanomodulator alleviates pyroptosis-associated lung injury in ARDS by selectively suppressing the cGAS–STING signaling axis

Injury and inflammation mediated by pulmonary endothelial cell pyroptosis are crucial factors in the progression of acute respiratory distress syndrome (ARDS). Although blocking the cyclic GMP‒AMP synthase (cGAS)–stimulator of interferon genes (STING) signaling pathway is a promi...