Jianjun Gu

Integrated Systems Toxicology Analysis and Molecular Dynamics Study Reveal the Potential Mechanism by which Benzo[a]pyrene Contributes to Depression in Lung Adenocarcinoma via RNASE1 Upregulation

Abstract Benzo[a]pyrene (Bap), a prominent carcinogen found in tobacco smoke and air pollution, is closely associated with lung adenocarcinoma (LUAD) and subsequent depression, though the mechanism underlying this comorbidity remains unclear. LUAD patients were categorized based...