Jianhua Shen

Orally available Colivin traps TRPV3 in an inactive state and suppresses intestinal inflammation

Abstract Transient receptor potential vanilloid 3 (TRPV3) is a non-selective cation channel highly expressed in the skin and intestine. While its roles in itch and skin inflammation are established, the physiological role of TRPV3 in the intestine remains relatively poorly unders...