Jiangyuan Zhou

Precision Medicine for Somatic Mutation-Driven Vascular Anomalies

Vascular anomalies, including proliferative vascular tumours and structural malformations, are largely driven by postzygotic somatic mutations that constitutively activate key signalling pathways, mainly the PI3K/AKT/mTOR and RAS/MAPK pathways. This molecular understanding has sh...