Jianfang Gai

A neutrophil-specific GSR integrates pattern recognition receptor in pathogenesis of neonatal late-onset sepsis: evidence from artificial intelligence-driven multi-omics and clinical validation

Abstract Background Neonatal late-onset sepsis (NS) is a life-threatening condition driven by a dysregulated host response to infection, where neutrophil dysfunction plays a pivotal role. Pattern recognition receptors (PRRs), as the frontline sensors of the innate immune system,...