Jiandong Jiang

hnRNPC facilitates coronavirus replication by directly binding the frameshift-stimulatory element of viral genomic RNA

Translation of key viral replicative proteins in coronaviruses requires a programmed –1 ribosomal frameshifting (–1 PRF) event controlled by the viral frameshift-stimulatory element (FSE). Although previous studies have analyzed host factor dependencies of coronaviruses, how host...