Jian Xiao

Liquid Metal Multi‐Functional Droplets Enabled High‐Performance Tumor Therapy With Four Synergistic Mechano‐Thermal‐Chemo‐Freezing Effects

ABSTRACT Cryoablation, which induces rapid intracellular ice crystal formation, has been widely used in clinics for treating various tumors, yet monotherapy yields limited efficacy due to inadequate elimination of tumor cells. Here, we proposed an effective synergistic strategy w...

A Metabo‐Reprogramming Niche Remodeling System Halts Osteoarthritis by Restoring the FGF21‐Arginine Axis

Osteoarthritis (OA), a global leading cause of chronic pain and disability, lacks disease-modifying osteoarthritis drugs (DMOADs) targeting its core pathogenesis. scRNA-seq of human OA cartilage showed marked depletion of a high-arginine-metabolism chondrocyte subpopulation drivi...