Jian-wen Li

Mast cell–derived SPP1 promotes colorectal cancer liver metastasis by suppressing BTG1-mediated JUN degradation

The role of mast cells in colorectal cancer (CRC) liver metastasis remains controversial. This study aimed to explore the effect of mast cells on the CRC liver metastasis and the underlying mechanism. The bulk-seq, scRNA-seq datasets and clinical samples were integrated to identi...