Jialu Chen

The Brucella effector protein BtpB facilitates STAT3 activation to regulate polarization in macrophages during infection

Brucella is a Gram-negative facultative intracellular pathogen that causes widespread zoonotic infections. Macrophages are crucial immune and antigen-presenting cells that differentiate into proinflammatory M1-type or anti-inflammatory M2-type cells in different microenvironments...