Jialin Wen

Olig2 downregulation mitigates early neurological deficits by modulating mitochondrial dynamics in neonatal hypoxic-ischemic brain injury

OBJECTIVE: Mitochondrial dysfunction and apoptosis are key pathological events in neonatal hypoxic-ischemic brain damage (HIBD). Oligodendrocyte transcription factor 2 (Olig2) is upregulated during the early phase of hypoxic-ischemic brain injury. This study aimed to investigate...