Jialin Feng

Cysteine-based molecular switches: a focus on KEAP1 and BACH1 in regulating the antioxidant response

Due to the chemical properties of their thiol groups and the surrounding amino acid environment, specific cysteines in proteins serve as the principal intracellular sensors for oxidants and electrophiles. In this review, we focus on the ubiquitin ligase substrate adaptor Kelch-li...