Jiajia Li

NAT10-mediated histone β-hydroxybutyrylation facilitates DNA replication and maintains genomic stability

Lysine β-hydroxybutyrylation (Kbhb) is a histone posttranslational modification derived from the ketone body β-hydroxybutyrate (BHB), but its role in DNA replication has remained unexplored. N-acetyltransferase 10 (NAT10) is known for RNA acetylation; whether it functions as a β-...