Jiahao Zhang

Substrate-Controlled Construction of Spiro-3-Oxoindolines and Eight-Membered-Ring Lactams under Bubbling Air Conditions

Abstract A substrate-controlled strategy for constructing spiro-3-oxoindolines and eight-membered-ring lactams from cyclic 2,3-dialkyl-substituted indoles has been developed, employing bubbling air to maximize the gas–liquid interfacial area. When tetrahydrocarbazoles and heteroa...