Jia Zhang

Engineered mesenchymal stem cell-derived extracellular vesicles overexpressing miR-146a alleviate neuroinflammation in Alzheimer's disease.

Alzheimer’s disease is an inflammatory neurodegenerative disease for which no effective clinical treatment currently exists. We have previously reported that mesenchymal stem cell–derived extracellular vesicles delay retinal degeneration by exerting anti-inflammatory effects thou...

Phenotype evolution in post-COVID-19 chronic cough and prediction of pulmonary fibrosis risk: a longitudinal cohort study leveraging multi-omics integration and deep learning

Post-coronavirus disease 2019 (COVID-19) chronic cough (PCC) is a frequent sequela, affecting approximately 20–30% of patients beyond 8 weeks, with a subset progressing to pulmonary fibrosis (PF). Most existing studies rely on static indicators, which limits monitoring of dynamic...