Jia-Shuai Zhong

ITGBL1 inhibits obesity and osteoporosis by maintaining adipogenic and osteogenic differentiation balance via the NEDD4–PPARγ–RUNX2 axis

Abstract Obesity and osteoporosis are two major public health concerns. Dysregulation of mesenchymal stem cell (MSC) lineage commitment has been closely linked to an imbalance between adipogenic and osteogenic differentiation, which leads to abnormal lipid accumulation and impair...