Jia-de Chen

Thromboxane A₂ analog U46619 promotes vascular smooth muscle cell apoptosis via Hippo pathway inhibition and its clinical relevance in aortic dissection

Apoptosis of human vascular smooth muscle cells (HAVSMCs) plays a pivotal role in the pathogenesis of aortic dissection (AD). In this study, we first observed in clinical samples that, compared with age- and sex-matched controls, patients with acute Stanford type A AD exhibited s...