Ji Min Lee

Poly-L-Lactic Acid Attenuates Fibrotic Remodeling During Cutaneous Wound Healing

Pathological hypoxia following cutaneous injury is a critical driver of wound chronicity and fibrotic remodeling. The nuclear receptor binding SET domain protein 2 (NSD2)/lysine demethylase 2A (KDM2A)–histone H3 lysine 36 dimethylation (H3K36me2) axis is a known regulator of hypo...

Current legislation and recommendations on ethical post-experimental care and disposition of laboratory animals: a call for global standards

The fate of laboratory animals once experiments end remains an ethical blind spot. This Comment compares the legislation governing the post-experimental care and disposition of laboratory animals—rehoming, reuse, setting free and tissue sharing—across the European Union, USA, UK...